top of page
  • shivakhened

HHS Small Business Transition Grant for New Entrepreneurs (R41/R42 Clinical Trial Not Allowed) - Applications Ongoing Until 04/05/27

Opportunity Title:

Small Business Transition Grant for New Entrepreneurs (R41/R42 Clinical Trial Not Allowed)


Department of Health and Human Services (HHS), National Institutes of Health (NIH)


Opportunity Number:




Through this Notice of Funding Opportunity (NOFO), the National Institutes of Health (NIH) aims to foster the advancement and accelerate the growth of early-career scientists transitioning to entrepreneurship by simultaneously supporting their entrepreneurial development and the conduct of research and development under their direction.

This NOFO supports small business concerns (SBCs) in employing and developing researchers as entrepreneurial Program Directors/Principal Investigators (PDs/PIs). In addition to supporting research and development efforts at the SBC, a major component of this NOFO is entrepreneurial training, mentoring, and career development of the PD/PI. Optimal PDs/PIs for this award are scientists and professionals with research, technology development, and/or healthcare delivery skills and experience, but limited entrepreneurial and independent (non-mentored) research leadership experience. PDs/PIs are expected to grow their entrepreneurial skillset while working in a small business to develop promising technologies and products that align with NIH's mission to improve health and save lives.

Pre-Application Webinar

NIH will hold a technical assistance webinar on June 11th, 2024 from 3:00 PM to 5:00 PM (Eastern Time)

The purpose of this webinar is to discuss the goals and objectives of the awarding components on the NOFO, highlight unique components of the application content and review criteria, and answer questions from attendees. Potential applicants are encouraged to submit their questions to NIH SEED (Small business Education and Entrepreneurial Development) at in advance of the webinar.



Small Businesses


Applications Ongoing Until April 05, 2027



Grant Management Associates has years of experience with opportunities like this one. Contact us today for a consultation.

21 views0 comments

Recent Posts

See All


bottom of page